General Information

  • ID:  hor005151
  • Uniprot ID:  P81627
  • Protein name:  Juvenile hormone-binding protein
  • Gene name:  JHBP
  • Organism:  Bombyx mori (Silk moth)
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Bombyx (genus), Bombycinae (subfamily), Bombycidae (family), Bombycoidea (superfamily), Obtectomera, Ditrysia, Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  DGDALLKPCKLGDMQKLSSA
  • Length:  20(1-20)
  • Propeptide:  DGDALLKPCKLGDMQKLSSA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Prevents juvenile hormone from being hydrolyzed by general esterases by combining with it specifically.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-P81627-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    AF-P81627-F1.pdbhor005151_AF2.pdbhor005151_ESM.pdb

Physical Information

Mass: 242955 Formula: C88H152N24O30S2
Absent amino acids: EFHINRTVWY Common amino acids: L
pI: 6.34 Basic residues: 3
Polar residues: 5 Hydrophobic residues: 6
Hydrophobicity: -32.5 Boman Index: -2634
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 88
Instability Index: -491.5 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  NA
  • Title:  Characterization of high affinity juvenile hormone binding protein in the hemolymph of Bombyx mori L.